Composition:

Each 1 ml contains:

Doxycycline hyclate                   116 mg
(Equivalent to doxycycline      100 mg)
Bromhexine HCI                        10 mg

Properties:

Doxycycline is a bacteriostatic agent that acts by interfering with the bacterial protein synthesis of sensitive species.
Doxycycline is a semi-synthetic tetracycline derived from oxytetracycline. It acts on the subunit 30S of the bacterial ribosome, to which it is linked reversibly, blocking the union between aminoacy l-tRNA (transfer RNA) to the mRNA-ribosome complex, preventing the addition of new aminoacids into the growing peptide chain and thus interfering with protein synthesis.
Doxycycline is active against Gram-positive and Gram-negative bacteria.
Spectrum of activity:
Streptococcus spp.
Staphylococcus aureus.
Chlamydia spp.
Mycoplasma spp.
Salmonella spp.
Pasteurella multocida.
Bordetella bronchiseptica.

Bromhexine hydrochloride.

Is a mucolytic agent used for treatment of respiratory disease where there is impaired mucociliary clearance and production of viscid mucous.

Indications:

Chickens (broilers):
Prevention and treatment of chronic respiratory disease (CRD) and mycoplasmosis caused by microorganisms sensitive to doxycycline.

Unweaned calves:

Treatment of respiratory infections caused by pasteurella multocida and mannheimia haemolytica.

Contra indications:

Do not use in case of hypersensitivity to tetracyclines.
Do not use in animals with hepatic dysfunction.
Do not administer to laying birds four weeks before the start of lay and during lay.
Do not use during pregnancy or lactation.

Side effects:

Allergic and photosensitivity reactions can occur. Intestinal flora may be affected if treatment is very prolonged, and this may result in digestive disturbance.

Dosage:

Chickens:

1 ml of Bromodoxy l/kg of body weight daily for 3-4 days (1ml/liter of drinking water for 4-5 days).

Unweaned calves:

1ml of Bromodoxyl /10kg of body weight daily for 3-4 days (1ml/liter of drinking water for 4-5 days).

Withdrawal times:

For meat & offal:
Chickens (broilers) : 7 days.
Eggs: Not permitted for use in laying birds producing eggs for human consumption.

Packaging:

Bottle:

500 ml or 1000 ml.