Bromycin

injectable solution

Composition: Each 1 ml contains:

Oxytetracycline Hydrochloride …………50 mg   (Equivalent to 46.3 mg Oxytetracycline)
Bromhexine Hydrochloride ……………3mg (Equivalent to 2.74 mg Bromhexine)
Lidocaine HCL …………………………..20mg

Properties:
Bromycin is a synergistic combination between Oxytetracycline and Bromhexine.
Oxytetracycline is a bacteriostatic agent that acts by interfering with the bacterial protein
synthesis of sensitive species. It acts on the subunit 30S of the bacterial ribosome, to which is
linked reversibly, blocking the union between aminoacyl-tRNA (transfer RNA) to the mRNA-
ribosome complex, preventing the addition of new amino acids into the growing peptide chain
and thus interfering with protein synthesis. Oxytetracycline is a broad spectrum antibiotic active
against aerobic and anaerobic Gram-positive and Gram-negative bacteria, mycoplasmas,
rickettsiae, chlamydiae, and even some protozoa.
Bromhexine is a mucolytic agent, used alone or in combination with antimicrobials for the
treatment of respiratory disease where there is impaired mucociliary clearance and production of
viscid mucous. It is also of value in achieving liquefaction and improving flow characteristics of
mucus by increasing the volume of bronchial secretion, modifies the pattern of mucosubstances
produced by the secretory cells, reduces the viscosity of the mucus and increases the
tracheobronchial ciliary activity.
The addition of Bromhexine to Oxytetracycline in Bromycin significantly increases the
antibiotic levels in the bronchial mucus by more than 40% so Bromhexine increases the efficacy
of Oxytetracycline against respiratory tract infections.

Indications:

  • Bromycin is indicated for the treatment of upper and lower respiratory tract infections caused by oxytetracycline sensitive Gram positive and Gram negative bacteria as well as Rickettsia, Mycoplasma and Chlamydia, especially in cases of retained mucoid secretions. These conditions include: sinusitis, laryngitis, tracheitis, bronchitis, pneumonia and emphysima.
  • Bromycin is also indicated for enteric, urogenital, soft tissues and mastitis infections.

Dosage:
1m/10kg B.wt (deep I/M).

Withdrawal Period:
Meat: 10 days
Not to be used in animals producing milk for human consumption.

Packs:
100 ml

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